The Agalliu laboratory is investigating several fundamental issues in the biology of the mammalian blood-brain barrier (BBB):

1) The mechanisms that govern the development and maintenance of the BBB.

2) How structural components of the BBB are affected in diseases of the brain and spinal cord where barrier function is impaired including stroke, MS and PANDAS.

3) The role of Wnt signaling in repairing the damaged BBB in CNS diseases.

Agalliu Lab Spring 2014
Agalliu Lab Spring 2014